Symbol
Name
ID

Ccdc88a
coiled coil domain containing 88A
MGI:1925177

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

abnormal neuron differentiation

abnormal neuronal precursor cell migration

abnormal olfactory bulb development

abnormal rostral migratory stream morphology

decreased brain size

abnormal dentate gyrus morphology

abnormal neocortex morphology

abnormal olfactory bulb morphology

abnormal olfactory bulb glomerular layer morphology

abnormal olfactory bulb granule cell layer morphology

abnormal olfactory bulb mitral cell layer morphology

abnormal olfactory bulb subventricular zone morphology

small olfactory bulb

abnormal GABAergic neuron morphology

abnormal dendritic spine morphology

decreased neuron number

reduced sensorimotor gating

abnormal excitatory postsynaptic currents

reduced long-term potentiation

decreased prepulse inhibition

Availability

Mouse Genotype

Ccdc88a^tm1Mat/Ccdc88a^tm1Mat

Ccdc88a^tm2.1Mat/Ccdc88a^tm2.1Mat

Ccdc88a^tm3.1Mat/Ccdc88a^tm3.1Mat

Ccdc88a^tm1Mat/Ccdc88a⁺

Ccdc88a^tm4.1Mat/Ccdc88a^tm4.1Mat
Tg(Nes-cre)1Kln/0 (conditional)

Ccdc88a^tm4.1Mat/Ccdc88a⁺
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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